Corticosteroid receptor genetic polymorphisms and stress responsivity

Addiction to cortisone was the subject of the 1956 motion picture, Bigger Than Life , produced by and starring James Mason . Though it was a box-office flop upon its initial release, [15] many modern critics hail it as a masterpiece and brilliant indictment of contemporary attitudes towards mental illness and addiction. [16] In 1963, Jean-Luc Godard named it one of the ten best American sound films ever made. [17] John F. Kennedy needed to regularly use corticosteroids such as cortisone as a treatment for Addison's Disease . [18]

Cells lining the gastrointestinal tract release serotonin when damaged by chemotherapy and radiation therapy. This serotonin binds to serotonin receptors on nerves that transmit impulses to the vomiting center within the brain, which in turn stimulates other nerves involved in the vomit reflex. 5-HT3 receptor antagonists prevent serotonin from binding to 5-HT3 receptors in the small intestine thereby reducing the likelihood of nausea and vomiting. The way 5-HT3 receptor antagonists work to prevent postoperative nausea and vomiting is less well understood.

Corticosteroid receptor genetic polymorphisms and stress responsivity

corticosteroid receptor genetic polymorphisms and stress responsivity

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corticosteroid receptor genetic polymorphisms and stress responsivitycorticosteroid receptor genetic polymorphisms and stress responsivitycorticosteroid receptor genetic polymorphisms and stress responsivitycorticosteroid receptor genetic polymorphisms and stress responsivitycorticosteroid receptor genetic polymorphisms and stress responsivity